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Session Details

Preventing GVHD: T-Cell Depletion versus Post-Transplant Cyclophosphamide
Thursday, May 30, 2024 05:00 PM - 06:00 PM  
Room 208-209
Clinic & Therapeutic Development
Roundtable
Organized by: ISCT Stem Cell Engineering Committee

Moderator(s)   
  • Duncan Purthill, MBBS FRACP FRCPA, Fiona Stanley Hospital, Australia
Panelist(s)
  • Alice Bertaina, MD, PhD, Stanford School of Medicine, United States
  • Orly Klein, MD, PhD, Stanford Schoool of Medicine, United States
  • Portia Smallbone, MBBS ( Stem cell transplant and cellular therapy fellow) MD Anderson Cancer Center
  • Madhavi Lakkaraja, Assistant Professor, Fred Hutch Cancer Research Center
While Post-Transplant Cyclophosphamide is emerging as standard of care in GVHD prophylaxis, debate whether novel T-cell depletion strategies and techniques should be implemented instead.

Key Learning Objectives

1. Where are we at with GVHD prophylaxis - is PTCy as good as it gets?
2. What advantages do ex vivo T-cell depletion strategies offer, and can they be further optimised?
3. What are the barriers to widespread roll-out of ex-vivo T-cell depletion for GVHD prophylaxis

Orly Klein
Clinical Assistant Professor
Lucile Packard Children's Hospital at Stanford
Panelist


Duncan Purtill
Haematologist
Fiona Stanley Hospital
Moderator


Alice Bertaina
Professor of Pediatrics
Stanford University
Panelist


Portia Smallbone
Stem Cell Transplant and Cellular Therapy Fellow
MD Anderson Cancer Center
Panelist


Madhavi Lakkaraja
Assistant Professor
Fred Hutchinson Cancer Center
Panelist