Miltenyi Biotec Presentation: Solutions For Gene Engineering of Hematopoietic Stem Cells in An Automated and Functionally Closed System
Thursday, May 30, 2024 12:15 PM - 12:30 PM
Exhibit Hall - Theatre A
Global Showcase Presentation
Presenter(s)
• Andreia Marques Gomes, Clinical Marketing, Regenerative Medicine, Miltenyi Biotec, GERMANY
Viral transduction of CD34+ cells is a promising approach to understand and treat inherited disorders such as sickle cell disease,-thalassemia, or primary immunodeficiencies.
However, up to now this remains a very challenging endeavor, and Miltenyi Biotec is dedicated to developing technologies to address these demands.
Miltenyi Biotec’s Hematopoietic Stem Cell Engineering process, facilitated by the CliniMACS Prodigy® Cell Manufacturing Platform, GMP-compliant consumables, reagents, and flow cytometric quality control solutions, can provide the necessary environment for GMP-compliant manufacturing of gene-engineered hematopoietic stem cells (HSCs).
In fact, the CliniMACS Prodigy Hematopoietic Stem Cell Engineering process automates manufacturing of gene-engineered HSCs by viral transduction of CD34+ cells.
Manufacturing takes place in sterile, single-use tubing sets connected to the CliniMACS Prodigy Instrument, providing a functionally closed system. Its robust performance reduces donor-associated variations while the flexible software allows for easy conversion of manual processes. Join this presentation to discover more details about our technologies.
• Andreia Marques Gomes, Clinical Marketing, Regenerative Medicine, Miltenyi Biotec, GERMANY
Viral transduction of CD34+ cells is a promising approach to understand and treat inherited disorders such as sickle cell disease,-thalassemia, or primary immunodeficiencies.
However, up to now this remains a very challenging endeavor, and Miltenyi Biotec is dedicated to developing technologies to address these demands.
Miltenyi Biotec’s Hematopoietic Stem Cell Engineering process, facilitated by the CliniMACS Prodigy® Cell Manufacturing Platform, GMP-compliant consumables, reagents, and flow cytometric quality control solutions, can provide the necessary environment for GMP-compliant manufacturing of gene-engineered hematopoietic stem cells (HSCs).
In fact, the CliniMACS Prodigy Hematopoietic Stem Cell Engineering process automates manufacturing of gene-engineered HSCs by viral transduction of CD34+ cells.
Manufacturing takes place in sterile, single-use tubing sets connected to the CliniMACS Prodigy Instrument, providing a functionally closed system. Its robust performance reduces donor-associated variations while the flexible software allows for easy conversion of manual processes. Join this presentation to discover more details about our technologies.
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