Extracellular Vesicles: Potential Tools for Targeted Gene Editing In Vivo
Thursday, May 30, 2024 09:15 AM - 10:15 AM
Room 217-219
Concurrent Session
Chair
Speakers
Extracellular Vesicles (EVs) can shuttle information between cells. While the significance of natural EV cargo delivery is debated, bioengineering techniques enable efficient loading of EVs, including with components of gene editing machineries. This session will highlight various strategies for loading EVs with gene editing components and discuss concepts for increasing their effective delivery for functional purposes.
- Bernd Giebel, PhD, University of Duisburg-Essen, Germany
Speakers
- Samir El-Andaloussi, PhD, Karolinska Institutet, Sweden, "Genetic engineering of extracellular vesicles for CNS delivery of gene editors"
- Olivier G. De Jong, PhD, Utrecht University, Netherlands, "Aptamer-Based Loading and Release STrategies for Extracellular Vesicle-Mediated CRISPR-CAS9 Delivery"
- Houjian Cai, PhD, University of Georgia, United States, "Deliver CRISPR Machinery via Extracellular Vesicles for Gene Therapy"
Extracellular Vesicles (EVs) can shuttle information between cells. While the significance of natural EV cargo delivery is debated, bioengineering techniques enable efficient loading of EVs, including with components of gene editing machineries. This session will highlight various strategies for loading EVs with gene editing components and discuss concepts for increasing their effective delivery for functional purposes.
