SONY GLOBAL SHOWCASE PRESENTATION Enabling GMP ready cell sorting with Sony CGX10 Cell Isolation System
Thursday, June 1, 2023 03:30 PM - 03:45 PM
Global Showcase Theater
Global Showcase Presentation
Enabling GMP ready cell sorting with Sony CGX10 Cell Isolation System
Chair
TBD
Presenter
Aditi Singh, PhD, Global Senior Marketing Manager, Sony Biotechnology Inc., USA
Ex vivo isolation and manufacturing of T-cells may result in complex mixtures of T-cell subtypes, which could lead to variable clinical outcomes. A current challenge in the field is the optimization of the manufacturing process; specifically obtaining well defined subsets of T-cells to enhance therapeutic outcomes. Young, undifferentiated T-cells are a rare population of T-cells, thought to enhance therapeutic outcome, which are characterized by a combination of transiently expressed cell surface markers. There are currently no GMP ready scalable solutions to isolate such T-Naïve (TN), T-Stem Cell Memory (TSCM), or T-Central Memory (TCM) T-cells. In this session, we will outline the utility of the CGX10, a GMP ready, closed cell sorting system from Sony, to isolate T-Naïve cells using multi-parametric selection, and share data on integration of the CGX10 Cell Isolation System in Closed CAR-T Cell Therapy Manufacturing
Chair
TBD
Presenter
Aditi Singh, PhD, Global Senior Marketing Manager, Sony Biotechnology Inc., USA
Ex vivo isolation and manufacturing of T-cells may result in complex mixtures of T-cell subtypes, which could lead to variable clinical outcomes. A current challenge in the field is the optimization of the manufacturing process; specifically obtaining well defined subsets of T-cells to enhance therapeutic outcomes. Young, undifferentiated T-cells are a rare population of T-cells, thought to enhance therapeutic outcome, which are characterized by a combination of transiently expressed cell surface markers. There are currently no GMP ready scalable solutions to isolate such T-Naïve (TN), T-Stem Cell Memory (TSCM), or T-Central Memory (TCM) T-cells. In this session, we will outline the utility of the CGX10, a GMP ready, closed cell sorting system from Sony, to isolate T-Naïve cells using multi-parametric selection, and share data on integration of the CGX10 Cell Isolation System in Closed CAR-T Cell Therapy Manufacturing
