|
Yufang Shi PhD
Director/Professor
Soochow University Institutes for Translational Medicine
China
|
Professor Yufang Shi, Ph.D., Member of Academia Europaea (2020), Director and Distinguished Professor of Institutes for Translational Medicine of Soochow University (2014), Vice-President of The First Affiliated Hospital of Soochow University (2014), Distinguished Professor of the University of Rome Tor Vergata (2019).
Dr. Shi received his Ph.D. in immunology from the University of Alberta (1992) and postdoctoral training at the University of Toronto. He was a faculty member at George Washington University and the American Red Cross Holland Laboratory (1995 to 2001). He was a University Professor and Tenured professor at Robert Wood Johnson Medical School, Rutgers University (2001 to 2008). Dr. Shi was the Director of the Institute of Health Sciences of the Chinese Academy of Sciences (2008 to 2014) and is currently the Director of Soochow University Institutes for Translational Medicine. In the early 1990s, a series of Dr. Shi’s publications creatively defined activation-induced cell death (AICD) in proliferative T cells, linking the "life" and "death" of immune cells with the regulation of immune homeostasis and establishing the "brake" concept of immune cell self-limitation to prevent excessive proliferation of antigen-activated immune cells. Based on the roles of inflammatory cytokine dynamics in licensing stem cells to regenerate tissues and to regulate immune responses, he established doctrines of "plasticity" and "empowerment" of MSCs in the pathogenesis and therapy of inflammatory diseases and tissue damage. Dr. Shi established a novel therapeutic theory of stem cell-mediated tissue repair. He found that stem cells in damaged tissues, in addition to regulating inflammation, secrete large amounts of growth factors to promote tissue regeneration and repair through cell empowerment, a revolutionary concept substituting the traditional one of cell replacement through stem cell direct differentiation. Dr. Shi devoted enormous amounts of time to the MSC committee of ISCT. He also served as an Editor-in-Chief of Cell Death and Disease, receiving editor of Cell Death and Differentiation, and a member of the Executive Board of Advanced Science. Dr. Shi’s more than 300 publications have appeared in Nature, Science, Nature Medicine, Cell Stem Cell, Immunity, and other journals with more than 46,000 citations. His h-index is currently 89.
Dr. Shi received his Ph.D. in immunology from the University of Alberta (1992) and postdoctoral training at the University of Toronto. He was a faculty member at George Washington University and the American Red Cross Holland Laboratory (1995 to 2001). He was a University Professor and Tenured professor at Robert Wood Johnson Medical School, Rutgers University (2001 to 2008). Dr. Shi was the Director of the Institute of Health Sciences of the Chinese Academy of Sciences (2008 to 2014) and is currently the Director of Soochow University Institutes for Translational Medicine. In the early 1990s, a series of Dr. Shi’s publications creatively defined activation-induced cell death (AICD) in proliferative T cells, linking the "life" and "death" of immune cells with the regulation of immune homeostasis and establishing the "brake" concept of immune cell self-limitation to prevent excessive proliferation of antigen-activated immune cells. Based on the roles of inflammatory cytokine dynamics in licensing stem cells to regenerate tissues and to regulate immune responses, he established doctrines of "plasticity" and "empowerment" of MSCs in the pathogenesis and therapy of inflammatory diseases and tissue damage. Dr. Shi established a novel therapeutic theory of stem cell-mediated tissue repair. He found that stem cells in damaged tissues, in addition to regulating inflammation, secrete large amounts of growth factors to promote tissue regeneration and repair through cell empowerment, a revolutionary concept substituting the traditional one of cell replacement through stem cell direct differentiation. Dr. Shi devoted enormous amounts of time to the MSC committee of ISCT. He also served as an Editor-in-Chief of Cell Death and Disease, receiving editor of Cell Death and Differentiation, and a member of the Executive Board of Advanced Science. Dr. Shi’s more than 300 publications have appeared in Nature, Science, Nature Medicine, Cell Stem Cell, Immunity, and other journals with more than 46,000 citations. His h-index is currently 89.