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Samuel Janes BSc MBBS FCRP MSc PhD F Med Sci
Director of the Division of Medicine, Faculty of Medical Sciences
University College London
Uk
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Sam is Director of Medicine at University College London, a division within the Faculty of Medical Sciences that encompasses 8 departments, over 20 centres and around 100 principal investigators across three campuses. His laboratory research, funded by Medical Research Council and Cancer Research UK programme grants focusses on the airways and examines both normal homeostasis and the earliest development of cancer. Major contributions include defining that normal airway homeostasis is governed by stochastic division of basal cell; showing that airways genetically damaged by smoking can resolve on quitting; mapping molecular architecture of pre-cancerous Squamous cell lesions, and identifying immunological abnormalities that allow precancerous lesions to progress to cancer. These achievements were recognised with his election to the Academy of Medical Sciences in 2021. He’s chief investigator of several trials ranging first-in-man trials of cell and gene therapies emanating from his own lab, to SUMMIT, the largest lung cancer screening trial in Europe recruiting over 13000 people. He works across the University, UCL Hospitals, UCLH Biomedical Research Centre and interacts closely with industry, ranging from trial delivery to venture capital funded drug discovery programmes.
His training began as an MRC Training Fellow performing a PhD, then a post-doctoral period working in the CRUK Lincoln’s Inn Fields Institute with Fiona Watt working on stem cell biology. He then moved as an MRC Clinician Scientist to UCL and later awarded a Wellcome Trust Senior Clinical Fellowship in October 2010 working on novel cell therapies for lung cancers resulting in a DPFS first-in-man award and in 2015 won his Wellcome Senior Fellowship renewal to study the genetic and cellular changes lung cancer pathogenesis. He’s a theme lead in the CRUK Lung Cancer Centre of Excellence, CRUK Early Detection Centre, CRUK City of London Centre and MRC UK Regenerative Medicine Platform and Longfond’s BREATH Consortia.
He works as a respiratory consultant at UCLH with a particular interest in lung cancer, mesothelioma, interventional and diagnostic bronchoscopy and early lung cancer detection. He’s been Head of UCL Respiratory, Vice-Chair of the National ‘Clinical Expert Group’ on Lung Cancer and Faculty of Medical Science Vice-Dean of Research at UCL.
His training began as an MRC Training Fellow performing a PhD, then a post-doctoral period working in the CRUK Lincoln’s Inn Fields Institute with Fiona Watt working on stem cell biology. He then moved as an MRC Clinician Scientist to UCL and later awarded a Wellcome Trust Senior Clinical Fellowship in October 2010 working on novel cell therapies for lung cancers resulting in a DPFS first-in-man award and in 2015 won his Wellcome Senior Fellowship renewal to study the genetic and cellular changes lung cancer pathogenesis. He’s a theme lead in the CRUK Lung Cancer Centre of Excellence, CRUK Early Detection Centre, CRUK City of London Centre and MRC UK Regenerative Medicine Platform and Longfond’s BREATH Consortia.
He works as a respiratory consultant at UCLH with a particular interest in lung cancer, mesothelioma, interventional and diagnostic bronchoscopy and early lung cancer detection. He’s been Head of UCL Respiratory, Vice-Chair of the National ‘Clinical Expert Group’ on Lung Cancer and Faculty of Medical Science Vice-Dean of Research at UCL.