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Andras Nagy PhD, HonD, FRSC
Senior Investigator
Lunenfeld-Tanenbaum Research Institute
Canada
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Dr. Andras Nagy is currently a Shawn Kimel Senior Scientist at the Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Professor in the Department of Obstetrics & Gynaecology and Institute of Medical Science at the University of Toronto and Professor at the Australian Regenerative Medicine Institute in Monash University, Melbourne. He holds a Tier I Canada Research Chair in Stem Cells and Regeneration. He is a Fellow of the Royal Society of Canada in the Life Sciences Division of the Academy of Science. Dr. Nagy is also a Foreign Member of the Hungarian Academy of Science, an Honorary Professor at the Helsinki University, and a Distinguished Professor at the Honk Kong University.
Dr. Nagy has made significant breakthroughs in developmental genetics, mouse and human pluripotent stem cell biology (both embryonic and reprogramming-induced), disease modelling and cell therapy approaches. His team created the first Canadian human embryonic stem cell lines in early 2000. In 2009, they developed the first method allowing the generation of iPS cell lines without any genetic change. Their approach allowed studying the reprogramming process at multiple OMICS levels, almost at daily resolution from differentiated cells to pluripotency. His current research has become even more translational by addressing and coming up with solutions for two significant hurdles of cell therapies: safety and allogeneic cell acceptance without the need for suppression of the immune system. Dr. Nagy’s research in cell-based therapy aims to advance medicine with a focus on treating incurable degenerative diseases, such as blindness, diabetes mellitus, arthritis, spinal cord injury, ageing, haemophilia, hypothyroidism, chronic pain, and multiple neurological disorders, including multiple sclerosis, depression, and bipolar disease.
Dr. Nagy has made significant breakthroughs in developmental genetics, mouse and human pluripotent stem cell biology (both embryonic and reprogramming-induced), disease modelling and cell therapy approaches. His team created the first Canadian human embryonic stem cell lines in early 2000. In 2009, they developed the first method allowing the generation of iPS cell lines without any genetic change. Their approach allowed studying the reprogramming process at multiple OMICS levels, almost at daily resolution from differentiated cells to pluripotency. His current research has become even more translational by addressing and coming up with solutions for two significant hurdles of cell therapies: safety and allogeneic cell acceptance without the need for suppression of the immune system. Dr. Nagy’s research in cell-based therapy aims to advance medicine with a focus on treating incurable degenerative diseases, such as blindness, diabetes mellitus, arthritis, spinal cord injury, ageing, haemophilia, hypothyroidism, chronic pain, and multiple neurological disorders, including multiple sclerosis, depression, and bipolar disease.